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  1. 31 sie 2000 · Here we report the complete sequence of P. aeruginosa strain PAO1. At 6.3 million base pairs, this is the largest bacterial genome sequenced, and the sequence provides insights into the basis...

  2. 13 paź 2022 · Sequencing of PAO1 revealed that P. aeruginosa has more regulatory genes than other sequenced bacteria genomes. The bacterium also has higher expression of transcriptional regulators in the LysR, AraC, ECF-σ, and two-component regulator families (Stover et al., 2000).

  3. 4 lip 2024 · Trajectories were inferred as the sequence of mutations in pathoadaptive genes since the emergence of the clone ancestor as implied by the PAO1-rooted tree stratified by CF and non-CF infection types.

  4. 22 cze 2021 · PAO1 has been the established choice for basic studies of P. aeruginosa physiology and metabolism (1), was the first P. aeruginosa strain to be mapped genetically (2), and was the first to have its genome sequenced (3).

  5. 11 sie 2022 · Pseudomonas aeruginosa is an opportunistic pathogenic bacterium for humans, animals, and plants, through producing different molecular factors such as biofilm, siderophores, and other virulence factors which favor bacterial establishment and infection in the host. In P. aeruginosa PAO1, the production of these factors is regulated by the ...

  6. 19 paź 2021 · P. aeruginosa strain PAO1 from log-phase culture (~ 0.1 OD 600) was seeded into wounds and then harvested for RNA-Seq after 2 and 6 h (H2 and H6, colonization), 24 h (H24, acute infection), 5...

  7. 21 lip 2022 · RNA-seq analysis was performed on total RNA extracted from Pseudomonas aeruginosa PAO1 WT grown either in planktonic conditions for 5 h at 37°C, under shaking (200 rpm) in ABTG medium or grown for 72 h in biofilm flow cell chambers under continuous feeding of ABTG medium.

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