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  1. 31 sie 2000 · At 6.3 million base pairs, this is the largest bacterial genome sequenced, and the sequence provides insights into the basis of the versatility and intrinsic drug resistance of P. aeruginosa.

  2. 13 paź 2022 · Sequencing of PAO1 revealed that P. aeruginosa has more regulatory genes than other sequenced bacteria genomes. The bacterium also has higher expression of transcriptional regulators in the LysR, AraC, ECF-σ, and two-component regulator families (Stover et al., 2000).

  3. 10 paź 2019 · The sequence of PAO1 is 6.3 Mbp in size (5570 predicted open reading frames), which in the year 2000, made it one of the largest bacterial genomes sequenced. It is important to note that there is phenotypic and genomic variation between PAO1 strains stored in different laboratories throughout the world, which is a consideration for the ...

  4. 25 cze 2022 · Abstract. Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that infects patients with cystic fibrosis, burn wounds, immunodeficiency, chronic obstructive pulmonary...

  5. 4 lip 2024 · Trajectories were inferred as the sequence of mutations in pathoadaptive genes since the emergence of the clone ancestor as implied by the PAO1-rooted tree stratified by CF and non-CF infection types.

  6. Pseudomonas aeruginosa (P. aeruginosa) is a Gram-negative opportunistic pathogen that infects patients with cystic fibrosis, burn wounds, immunodeciency, chronic obstructive pulmonary disorder...

  7. 22 cze 2021 · Sequence reads were mapped to the PAO1 genome after removing the bases corresponding to the transposon end (reads without transposon sequence were discarded), and total reads per unique insertion (location and direction) were tallied for each sample.

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