Search results
Is diarrhea the only sign of PLE? Diarrhea is one common sign of PLE. The diarrhea may come and go, may be continuous, or may be the consistency of water. But some dogs with PLE have normal stools. Dogs will also have a difficult time holding their weight, and they may become lethargic.
27 lip 2021 · Symptoms of Protein-Losing Enteropathy in Dogs. The most common clinical signs associated with protein-losing enteropathy are primary GI signs like vomiting and diarrhea. Chronic cases often result in excessive weight loss, dehydration, and generalized weakness.
6 lip 2023 · Key points. Canine protein-losing enteropathy (PLE) is a syndrome that occurs as a consequence of various disorders. Chronic inflammatory enteropathy and intestinal lymphangiectasia are the most common causes of canine PLE.
Protein-losing enteropathy (PLE) is a syndrome caused by a variety of gastrointestinal diseases causing the enteric loss of albumin and globulin. 1,2 Intestinal inflammation, infiltration, ulceration, blood loss, and primary or secondary lymphangiectasia are well documented causes of PLE (Table 1). If left untreated, the final outcome of PLE is ...
Key points. Protein-losing enteropathies (PLE) cause enteric protein loss, principally albumin, and most often reflect small intestinal disease. Clinical signs of PLE usually result from intestinal dysfunction (vomiting, diarrhea, weight loss) and/or hypoalbuminemia (body cavity effusion, peripheral edema).
The major causes of PLE in juvenile dogs tend to be parasites and chronic intussusception. All of these cause primarily small-bowel diarrhoea, but may sometimes also cause vomiting or large-bowel diarrhoea. Not uncommonly, GI signs may be absent or anorexia and abdominal pain can be found.
Protein-losing enteropathy is common in dogs but rare in cats. In the vast majority of cases, it is associated with inflammatory bowel disease, intestinal lymphoma, or intestinal lymphangiectasia. The diagnosis is based on identification of hypoalbuminemia and ruling out urinary loss and liver failure.
