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1. www.novoprolabs.com › support › articlesHow to convert human dose to animal dose? NovoPro

   www.novoprolabs.com › support › articles

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   Therefore, extrapolation of dose from animals to humans needs consideration of body surface area, pharmacokinetics, and physiological time to increase clinical trial safety. Human equivalent dose calculation based on body surface area*

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2. pmc.ncbi.nlm.nih.gov › articles › PMC4804402A simple practice guide for dose conversion between animals and...

   pmc.ncbi.nlm.nih.gov › articles › PMC4804402

   Understanding the concept of extrapolation of dose between species is important for pharmaceutical researchers when initiating new animal or human experiments. Interspecies allometric scaling for dose conversion from animal to human studies is one ...

3. www.jbclinpharm.org › articles › a-simple-practice-guide-for-dose-conversionA simple practice guide for dose conversion between animals and...

   www.jbclinpharm.org › articles › a-simple-practice-guide-for-dose-conversion

   The dose by factor method applies an exponent for body surface area (0.67), which account for difference in metabolic rate, to convert doses between animals and humans.

4. www.researchgate.net › publication › 361713536_Dose_Conversion_Between_Animals_andDose Conversion Between Animals and Humans: A Practical Solution

   www.researchgate.net › publication › 361713536_Dose_Conversion_Between_Animals_and

   30 cze 2022 · The standard conversion factors are included to allow dose translation between animals to humans and humans to animals expressed either in mg/kg or mg/m2. The estimation of a safe starting dose...

5. www.woundsource.com › product › proteinexProteinex® - WoundSource

   www.woundsource.com › product › proteinex

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   Proteinex® provides 18 or 26 grams of hydrolyzed liquid protein per serving. Great taste, easy to swallow, highly concentrated liquid form. Provides fast absorption of proteins, amino acids, and malic acid.

6. www.ijper.org › sites › defaultDose Conversion Between Animals and Humans: A Practical Solution

   www.ijper.org › sites › default

   dose translation between animals to humans and humans to animals expressed either in mg/kg or mg/m 2. The estimation of a safe starting dose is important to ensure the safety and tolerability of humans during phase-I clinical trials. Keywords: Starting dose, Body surface area, Dose translation, Human equivalent dose,

7. pubmed.ncbi.nlm.nih.gov › 27057123A simple practice guide for dose conversion between animals ... -...

   pubmed.ncbi.nlm.nih.gov › 27057123

   This review provides basic information about translation of doses between species and estimation of starting dose for clinical trials using allometric scaling. The method of calculation of injection volume for parenteral formulation based on human equivalent dose is also briefed.