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25 gru 2017 · This document discusses gene motifs and algorithms for finding motifs in DNA sequences. It defines a gene as a segment of DNA that encodes a protein, and a motif as a conserved element in a protein sequence alignment that correlates with a function.
4 mar 2024 · Motifs • small regions of protein three-dimensional structure or amino acid sequence shared among different proteins. • Signatures of protein families and can often be used as tools for the prediction of protein function.
13 lis 2019 · This document discusses motifs and domains in proteins. It defines motifs as short conserved regions related to function, such as binding sites, that are not detectable by sequence searches. There are sequence motifs consisting of nucleotide or amino acid patterns, and structural motifs formed by amino acid spatial arrangements.
6 kwi 2019 · DNA Motif and protein domain discovery. Presented by: Deeter Neumann Peter St. Andre. PDB; human enhancer binding protein. PDB; zinc finger 224. Outline. What are DNA motifs & proteins domains? Their importance and function motif algorithms locating domain/motif experimentally.
6 lis 2014 · Protein Domains • In additional to protein short motifs, proteins are characterized by Domains. • Domains are long motifs (30-100 aa) and are considered as the building blocks of proteins (evolutionary modules).
22 lip 2014 · Motif • Set of similar substrings, within a family of diverged sequences. Motif long DNA or protein sequence. Why identify motifs? • In proteins • Identify functionally important regions of a protein family • Find similarities to known proteins • In DNA • Discover how genes are regulated.
Focuses of this lecture: Transcription factor binding sites, which are short DNA regulatory sequences that frequently appear at specific genomic locations. Some of them are conserved across species. Protein domains, which are similar sub-sequences on different proteins that serve particular functions.