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22 lut 2024 · Finding a specific sequence motif in a protein or nucleic acid suggests that it may have the function associated with the motif; i.e., it can be used to predict function (s). The sequence motif search options are available from the Advanced Search Query builder (Figure 1).
- Structure Similarity Search
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- Attribute Details
Attribute Details - Sequence Motif Search - RCSB PDB
- Attribute Search
Attribute Search - Sequence Motif Search - RCSB PDB
- Structure Motif Search
Structure Motif Search - Sequence Motif Search - RCSB PDB
- Sequence Similarity Search
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Chemical Sketch Tool - Sequence Motif Search - RCSB PDB
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Motif discovery plays a vital role in identification of Transcription Factor Binding Sites (TFBSs) that help in learning the mechanisms for regulation of gene expression. Over the past decades, different algorithms were used to design fast and accurate motif discovery tools.
1 sie 2023 · Protein sequence motifs are patterns of residues with different structural and/or functional features. They were recognized with protein multiple sequence/structural alignment methods as typical conserved signatures of protein families [1].
Motifs • Motif is a region (a subsequence) of protein or DNA sequence that has a specific structure • Motifs are candidates for functionally important sites • Presence of a motif may be used as a base of protein classification
1 cze 1996 · Genome sequencing provides the basis for a systematic analysis of all motifs that are present in a particular organism. A systematically derived motif database is therefore feasible, allowing the classification of the majority of the newly appearing protein sequences into known families.
7 gru 2020 · These results document that our approach provides support for facile searching of structural motifs in nucleic acids, and also indexes occurrences in homo- and heteromeric biological assemblies, including protein-nucleic acid complexes.
23 lip 2012 · In this paper, we describe an extension of DeepView/Swiss-PdbViewer through which structural motifs may be defined and searched for in large protein structure databases, and we show that common structural motifs involved in stabilizing protein folds are present in evolutionarily and structurally unrelated proteins, also in deeply buried location...
