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PSSMSearch - is a web application to discover novel protein motifs (SLiMs, mORFs, miniMotifs) and PTM sites. PSSMSearch analyses proteomes for regions with significant similarity to a specificity determinant model built from a set of aligned functional peptides.
22 lut 2024 · Finding a specific sequence motif in a protein or nucleic acid suggests that it may have the function associated with the motif; i.e., it can be used to predict function (s). The sequence motif search options are available from the Advanced Search Query builder (Figure 1).
Motifs • Motif is a region (a subsequence) of protein or DNA sequence that has a specific structure • Motifs are candidates for functionally important sites • Presence of a motif may be used as a base of protein classification
A biological motif, broadly speaking, is a pattern found occurring in a set of biological sequences, such as in DNA or protein sequences. A motif could be an exact sequence, such as [latex]\texttt{TGACGTCA}[/latex], or it could be a degenerate consensus sequence, allowing for ambiguous characters, such as [latex]\texttt{R}[/latex] for [latex ...
Motif discovery plays a vital role in identification of Transcription Factor Binding Sites (TFBSs) that help in learning the mechanisms for regulation of gene expression. Over the past decades, different algorithms were used to design fast and accurate motif discovery tools.
MOTIF Search: Search Motif Library Search Sequence Database Generate Profile KEGG2; Help: Enter query sequence: (in one of the three forms) Sequence ID (Example) mja:MJ_1041: Local file name: Sequence data: Select motif libraries : Databases: Cut-off score (Click each database to get help for cut-off score) Pfam * E-value NCBI-CDD All
17 lip 2008 · Protein structures have conserved features – motifs, which have a sufficient influence on the protein function. These motifs can be found in sequence as well as in 3D space. Understanding of these fragments is essential for 3D structure prediction, modelling and drug-design.
