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20 wrz 2021 · Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of promethazine for the treatment of nausea and vomiting poses little risk to the breastfed infant. With repeated doses, observe infants for excess sedation.
Breastfeeding while taking promethazine: Studies have not been done to see if promethazine can get into breastmilk. Promethazine can cause sleepiness in adults and might have the same effect in a nursing baby.
5 cze 2024 · Based on minimal excretion of other phenothiazine derivatives, it appears that occasional short-term use of promethazine for the treatment of nausea and vomiting poses little risk to the breastfed infant. With repeated doses, observe infants for excess sedation.
The LactMed® database contains information on drugs and other chemicals to which breastfeeding mothers may be exposed. It includes information on the levels of such substances in breast milk and infant blood, and the possible adverse effects in the nursing infant.
29 wrz 2021 · One study including 17 women investigated the impact of chlorpheniramine or promethazine on prolactin levels. 38 Another study investigated possible adverse reactions in breastfed infants exposed to medications in general 20 and included 85 breastfed infants exposed to antihistamines.
1 kwi 2019 · Breast milk is the most beneficial nutrition a mother can give her infant. Fortunately, the dose of most drugs transferred into milk is small and does not lead to clinically significant effects on the infant. In almost all instances, the mother should be advised to continue breastfeeding.
Antihistamine use during breastfeeding with focus on breast milk transfer and safety in humans: A systematic literature review.