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Firstly, we describe which drugs should be avoided in LQTS and then we move on the specific topic of the review describing the anaesthesiological management of patients with LQTS. Certain drugs, including some anesthetics, are known to contribute to QT prolongation.
A comprehensive list of conditions and drugs that may prolong the QT interval, cause torsade de pointes (TdP) and long QT syndrom (LQTS) is presented below. With regards to drugs, the risk of QT prolongation and TdP varies markedly across the list but tends to be rather similar within a drug class.
2 lip 2023 · Describe the possible mechanisms by which drugs might prolong the QT interval. Summarize the at-risk patient populations for QT-prolonging medications. Review the necessary monitoring when patients are using medications that can cause QT prolongation.
absence of drugs from these lists should not be considered an indication that they are free of risk of QT prolongation or torsades de pointes. Many medicines have not been tested for this risk in patients, especially those with congenital long QT syndrome.
11 lip 2016 · Drug-induced prolongation of the QT interval is a significant and potentially dangerous drug toxicity that can lead to the polymorphic ventricular tachycardia TdP.
Prolongation of the QT interval can lead to a life threatening arrhythmia known as torsades de pointes. Over the last few years a number of warnings have highlighted the risk of QT prolongation with citalopram, domperidone, ondansetron, hydroxyzine and quinine.
Below is a list of alternatives to some QT prolonging drugs. All patients with Long QT syndrome should speak to a health care provider or pharmacist prior to taking any new over-the-counter or prescription drug.
