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1. www.biopharma-excellence.com › 2021/6/29-how-to-create-a-smart-integrated-drugHow to create a smart integrated drug development plan including...

   www.biopharma-excellence.com › 2021/6/29-how-to-create-a-smart-integrated-drug

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   29 cze 2021 · Important questions guiding the nonclinical development are for example (1) how does the drug work and for how long, (2) are there relevant animal models available for pharmacology and safety assessment (3) what is an appropriate dose and regimen, (4) what are potential safety concerns and uncertainties, and (5) how can the risks and ...

   • Risk Management Plans for ATMPs

     Neutralising Antibodies, or NAbs, are a subclass of...

   • Requests for Proposals – Get The Best Value When Asking for Services

     You need a service for a certain aspect of your...

   • Fit-for-purpose Immunogenicity Assays: What to Consider During Assay Development and Validation

     In general, the ADA assay should be developed and validated...

   • Transposons in Gene Therapy

     Historically, γ-retroviral vectors were associated with...

   • Neutralizing Antibody Assay Development – a Key Consideration for Immunogenicity Packages

     For example, products which ... How to create a smart...

   • Press Releases

     Press Release Biopharma Excellence’s push for African...

2. liveonbiolabs.com › in-vivo-vs-in-vitro-modelsIn Vivo vs. In Vitro Models Differences & Applications

   liveonbiolabs.com › in-vivo-vs-in-vitro-models

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   Understand the key differences between in vivo and in vitro models and their applications in preclinical research and drug development.

3. www.ncbi.nlm.nih.gov › pmc › articlesComplex in vitro model: A transformative model in drug...

   www.ncbi.nlm.nih.gov › pmc › articles

   1 lut 2024 · This review aimed to comprehensively examine and analyze the various types, manufacturing techniques, and applications of CIVM in the domains of drug discovery, drug development, and precision medicine.

4. www.ncbi.nlm.nih.gov › pmc › articlesBrain-on-a-Chip: Characterizing the next generation of advanced...

   www.ncbi.nlm.nih.gov › pmc › articles

   30 lip 2021 · Abstract. The complexity of the human brain creates significant, almost insurmountable challenges for neurological drug development. Advanced in vitro platforms are increasingly enabling researchers to overcome these challenges, by mimicking key features of the brain's composition and functionality.

5. link.springer.com › article › 10Welcome to In vitro models | In vitro models - Springer

   link.springer.com › article › 10

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   28 paź 2021 · In vitro models is a hybrid journal published by Springer (part of Springer Nature), and it is the first of the kind focusing on research that deals with the upcoming and impactful field of in vitro models.

6. www.nature.com › articles › s41598/018/34280-3Development and validation of an in vitro model system to study...

   www.nature.com › articles › s41598/018/34280-3

   29 paź 2018 · We attempted to develop an in vitro co-culture system using the hESC-derived sensory neurons and human donor Schwann cells to provide a unique model to study the factors that influence...

7. www.researchgate.net › publication › 358381037_Perspectives_on_the_Evaluation_andPerspectives on the Evaluation and Adoption of Complex in Vitro...

   www.researchgate.net › publication › 358381037_Perspectives_on_the_Evaluation_and

   21 sty 2022 · Abstract. Complex in vitro models (CIVM) offer the potential to improve pharmaceutical clinical drug attrition due to safety and/or efficacy, but for this technology to have an impact, the ...