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19 sie 2022 · Abstract. The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
It depicts the emergence of the first vivisection studies by classical Greek physicians, the absence of animal-based research—along with most medical and scientific research—across the Middle Ages, its resurgence in the Renaissance onwards, and the rapid increase in animal studies following the rise of science-based physiology and medicine ...
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
Animal testing has been central to pre-clinical drug development for several decades, yet there remains no substantial, robust, published evidence that this has a scientific basis—i.e. that these tests are reliably predictive of human responses, both with respect to efficacy and toxicity/safety.
11 paź 2022 · In this article, I present four examples of animal tests that were introduced in the past to protect patients and consumers, and I discuss attempts to replace those animal tests with other...
9 sty 2024 · The Beyond Animal Testing Index (BATI) is a benchmarking instrument designed to provide insight into the activities and contributions of research institutes to the transition to animal free innovation.
1 sie 2023 · It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated. It is important that we are more critical about the use of animals in research and begin to transition to human-relevant models, which can be addressed by NAMs.
