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25 lip 2019 · From the Archives: Animal Research. Every year, scientists use millions of animals—mostly mice and rats—in experiments. The practice provokes passionate debates over the morality and efficacy of such research—and how to make it more humane.
19 sie 2022 · The contemporary pharmaceutical industry is voicing growing concerns about the translatability and reproducibility of animal models. In addition, the usefulness of certain of the required regulatory safety tests in animals is being increasingly questioned.
1 sie 2023 · Such significant failures in clinical trials raise the question: what scientific evidence do we have that animal tests are the best way to predict and protect human health? It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated.
1 cze 2011 · Medical advances should be weighed up against the delays and tragedies caused by reliance on animal experiments – the thalidomide disaster whereby tens of thousands of children were born with severe deformities not predicted in animal tests, to name one of the most famous, but there are many others.
21 paź 2020 · Here we present a mini-review on the development of animal testing, as well as on alternative in vitro and in silico methods, that may at least partly replace animal experiments in the near future.
16 paź 2019 · The latest news and opinions in animal testing from The Scientist, the life science researcher's most trusted source of information.
Russell and Burch introduced the principles of replacement, reduction, and refinement of animal experimentation in 1959 in their groundbreaking book, The Principles of Humane Experimental Technique, to eradicate inhumanity towards non-human animals (hereinafter referred to as animals).