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19 sie 2022 · Regulatory animal experiments are demanded as part of the medicine and vaccine development process. Pharmaceutical companies typically test their medicinal products following a tripartite testing procedure: preclinical, clinical (Phase I, II and III) and post-marketing surveillance.
1 sie 2023 · Such significant failures in clinical trials raise the question: what scientific evidence do we have that animal tests are the best way to predict and protect human health? It is about time the paradigm of animal testing as a “gold standard” in medicine was challenged, researched, and re-evaluated.
1 cze 2023 · Nature Medicine - The US Food and Drug Administration has reduced requirements for preclinical animal testing, leading to a surge of interest in organoids, tissue chips and in silico testing.
7 wrz 2011 · This Overview provides a brief summary of the ethical and scientific considerations regarding the use of animals in research and testing, some of which are highlighted in the accompanying Collection. Analysis and Discussion
19 kwi 2024 · Alternative solutions have recently been investigated to address the problems of animal testing. Some of these technologies are related to stem cell technologies, such as organ-on-a-chip, organoids, and induced pluripotent stem cell models.
1 paź 2020 · This judgment has important medico-legal and bioethics implications and raises some questions about animal testing: is it justified to “sacrifice” animal lives? Is there any real benefit from animal testing? When is it ethical to use animals for research and when is it not? Are there good alternatives?
27 kwi 2022 · Non-animal technologies and methods for assessing chemical hazards, medical risks and therapies are called new approach methodologies (NAMs).
