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1. www.ncbi.nlm.nih.gov › pmc › articlesEssential Thrombocythemia in Children and Adolescents

   www.ncbi.nlm.nih.gov › pmc › articles

   6 gru 2021 · The present paper reviews current ideas on different manifestations of thrombocytosis in children and the main differences between primary and secondary thrombocytosis. Diagnostic and therapeutic implications are discussed.

   • Essential Thrombocytosis - StatPearls - NCBI Bookshelf

     According to the World Health Organization, essential...

   • Causes of Thrombocytosis: A Single-center Retrospective Study of 1,202 ...

     Thrombocytosis can occur as a primary event accompanying...

2. www.ncbi.nlm.nih.gov › books › NBK539709Essential Thrombocytosis - StatPearls - NCBI Bookshelf

   www.ncbi.nlm.nih.gov › books › NBK539709

   6 sie 2023 · According to the World Health Organization, essential thrombocytosis can be diagnosed when the platelet count is over 45,0000/microliter, and there is either a Janus kinase 2 (JAK2), Calreticulin (CALR) or myeloproliferative leukemia virus oncogene (MPL) mutation, lacking clonal or reactive causes.

3. www.ncbi.nlm.nih.gov › pmc › articlesCauses of Thrombocytosis: A Single-center Retrospective Study of...

   www.ncbi.nlm.nih.gov › pmc › articles

   11 lis 2022 · Thrombocytosis can occur as a primary event accompanying hematological diseases or as a secondary event. Since the publication of the World Health Organization classification in 2008, thrombocytosis is now generally defined as a platelet count above 450×10 9 /L.

4. www.uptodate.com › contents › approach-to-the-patient-with-thrombocytosisApproach to the patient with thrombocytosis - UpToDate

   www.uptodate.com › contents › approach-to-the-patient-with-thrombocytosis

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   19 sie 2022 · Thrombocytosis refers to an increased platelet count which, in this review, is >450,000/microL (>450 x 10 9 /L). This topic discusses our approach to the adult or child with unexplained thrombocytosis.

5. link.springer.com › content › pdfThrombocytosis in children and adolescents classification,...

   link.springer.com › content › pdf

   Primary hereditary thrombocytosis may be caused by germline mutations within the genes encoding key regulators of thrombopoiesis, i.e., thrombopoietin (THPO) and its receptor c-MPL (MPL) or the receptor’s effector kinase Januskinase2 (JAK2).

6. link.springer.com › article › 10Thrombocytosis in children and adolescents—classification,...

   link.springer.com › article › 10

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   Primary thrombocytosis in children is rare compared to secondary forms. Important triggers of secondary thrombocytosis include infection and inflammation as well as iron deficiency, which may be identified through clinical examination and basic laboratory assessment.

7. ascopubs.org › doi › 10Survival and Disease Progression in Essential Thrombocythemia Are...

   ascopubs.org › doi › 10

   11 lip 2011 · The WHO diagnostic criteria underscore the role of bone marrow (BM) morphology in distinguishing essential thrombocythemia (ET) from early/prefibrotic primary myelofibrosis (PMF). This study examined the clinical relevance of such a distinction.