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Pregabalin, sold under the brand name Lyrica among others, is an anticonvulsant, analgesic, and anxiolytic amino acid medication used to treat epilepsy, neuropathic pain, fibromyalgia, restless legs syndrome, opioid withdrawal, and generalized anxiety disorder (GAD).
Pregabalin (PGB) is a newer generation gabapentinoid which followed the use of gabapentin (GBP). Originally synthesized over four decades ago [ Satzinger et al. 1976 ], GBP was initially developed for use as an adjuvant antiepileptic drug (AED).
2 maj 2024 · This activity prioritizes understanding pregabalin's mechanism of action, adverse event profile, and other pivotal factors such as off-label uses, dosing, monitoring, and pertinent interactions. The article also discusses the intricacies of administration, pharmacokinetics, and clinical toxicology, spotlighting the imperative role of the ...
2 maj 2024 · This activity prioritizes understanding pregabalin's mechanism of action, adverse event profile, and other pivotal factors such as off-label uses, dosing, monitoring, and pertinent interactions. The article also discusses the intricacies of administration, pharmacokinetics, and clinical toxicology, spotlighting the imperative role of the ...
21 sty 2019 · We identified several guidelines that recommend the use of pregabalin for treatment of neuropathic pain, and some of their specifications are consistent with our results.
Pregabalin is an anticonvulsant drug used to treat neuropathic pain, fibromyalgia, and partial-onset seizures. It is structurally similar to GABA and binds to calcium channels. Learn more about its indications, dosage, and side effects.
1 cze 2005 · Basis of discovery. Pregabalin is closely related to gabapentin (Neurontin; Pfizer), an alkylated analogue of γ-amino-butyric acid (GABA), the main inhibitory neurotransmitter in the central...
