Search results
14 maj 2021 · Prazosin was found to be statistically significantly more effective than placebo in improving sleep quality [p=0.987, 95% confidence interval (CI): 0.324–1.651] and reducing overall PTSD symptoms (p=0.699, 95% CI: 0.139–1.260) and sleep disorders in particular (p=0.799, 95% CI: 0.391–1.234).
Prazosin has been recommended for treatment of PTSD-associated nightmares (Level A) , but the recent highly recognized PACT trial reported that prazosin did not alleviate distressing dreams nor improve sleep quality in military veterans with chronic PTSD .
9 lut 2021 · In this data set, twice daily prazosin substantially reduced not only nightmares and sleep disruption, but the majority of hyperarousal symptoms, with some evidence of efficacy for avoidance symptoms.
7 lut 2018 · In randomized trials, prazosin, an α 1 -adrenoreceptor antagonist, has been effective in alleviating nightmares associated with post-traumatic stress disorder (PTSD) in military veterans.
Background: Prazosin has been an accepted treatment for patients with post-traumatic stress disorder (PTSD) who experience sleep disturbances, including nightmares. Results of a recent large randomized control trial did not find benefit of prazosin vs placebo in improving such outcomes.
4 maj 2020 · Background: In randomized trials, prazosin, an α1-adrenoreceptor antagonist, has been effective in alleviating nightmares associated with post-traumatic stress disorder (PTSD) in military...
1 mar 2016 · We found that prazosin was statistically significantly more effective than placebo in improving sleep quality [g= 0.987, 95% confidence interval (CI): 0.324–1.651] and in reducing overall PTSD symptoms (g= 0.699, 95% CI: 0.139–1.260) and sleep disturbances in particular (g= 0.799, 95% CI: 0.391–1.234).
