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14 mar 2019 · Purpose of Review. Overwhelming evidence indicates that reduction of blood low-density lipoprotein cholesterol (LDL-C), ratio of LDL-C/HDL-C, and TG/HDL-C ameliorate the occurrence of atherosclerotic cardiovascular disease. Long-chain alcohols and aldehydes known generically as policosanol (PC) and policosanal have attracted attention from ...
1 wrz 2022 · Policosanol, a well-tolerated long-chain aliphatic alcohol has been proven to be effective against the components of metabolic syndrome (namely dyslipidemia, diabetes, hypertension, and obesity) even when used for a long period with minimal or no adverse effects. Objective.
1 sie 2019 · Policosanol contains a mixture of concentrated primary aliphatic alcohols extracted from sugar cane wax and is recognized as a cholesterol-lowering drug but previous studies reported that it could be helpful for reducing blood pressure as well.
1 sty 2024 · Its main component is octacosanol (up to 70% w/w), which is responsible for its lipid-lowering effects. Other components are triacontanol, hexacosanol, dotriacontanol, heptacosanol, tetracosanol, tetratriacontanol, and nonacosanol.
9 sty 2024 · The brain regulates ABP pressure through sympathetic, parasympathetic, and neuroendocrine systems. These functions are controlled by an increasingly well-defined interconnected central network that is designed to sense and mitigate perturbations in cardiovascular homeostasis.
Policosanol has been found to inhibit cholesterol biosyn-thesis by indirectly regulating the activity of hydrox-ymethylglutaryl coenzyme A (HMG-CoA) reductase and by an enhancement of receptor-dependent LDL processing [28–31].
26 wrz 2017 · Policosanol has been reported to improve blood pressure, lipid profile, and HDL functionality via inhibition of cholesteryl ester transfer protein (CETP) both in vitro and in vivo in zebra sh and human models.
