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To treat the emotional symptoms of PMDD (e.g., depression, tearfulness, mood swings, anxiety, anger, irritability, fatigue, difficulty concentrating), the majority of experts recommend antidepressant medications.
PMDD is a cyclical mood disorder affecting a subset of menstruating women with a disease burden comparable to other depressive disorders. A significant body of evidence supports the use of SSRIs dosed either continuously or during the luteal phase as an effective first-line treatment for PMDD.
Based on theories regarding the underlying causes of PMDD, two main treatment options have been developed: (1) targeting the hypothalamus-pituitary-ovary axis by abolishing fluctuations in gonadal hormone levels (e.g. GnRH analogues, oestradiol, combined oral contraceptives (COCs)) and (2)
Premenstrual dysphoric disorder (PMDD), a severe form of premenstrual syndrome (PMS), is diagnosed by the pattern of symp-toms. According to a report by the Committee on Gynecologic Practice of the American Col-lege of Obstetricians and Gynecologists, 1 up to From 2 to 10 percent of women of reproductive age have severe distress and dysfunction
30 cze 2021 · Once a diagnosis of PMDD is established, first-line treatments include SSRIs, oral contraceptives, and cognitive-behavioral treatment. PMDD treatment with SSRIs is unique from other affective disorders, as intermittent dosing and use of lower dosages are possible.
Treatment strategies ranging from nonpharmacologic approaches such as dietary modification and aerobic exercise to pharmacologic interventions such as antidepressants, anxiolyt- ics, and agents to suppress ovulation are examined.
Premenstrual dysphoric disorder (PMDD) is an affective disorder characterized by mood symptoms that initiate during the luteal (premenstrual) phase of the menstrual cycle and resolve with menses onset [1,2]. As an affective disorder, primary PMDD symptoms include irritability, depressed mood, anxiety, and mood lability.
