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25 wrz 2024 · This manual provides comprehensive information on plague epidemiology and recommendations for surveillance, diagnosis, clinical management, and prevention. It also aligns with WHO's proposals from the 75th World Health Assembly to enhance global health emergency preparedness and response.
- WHO guidelines for plague management: revised recommendations for the ...
Three key areas selected to be addressed in this guideline:...
- WHO guidelines for plague management: revised recommendations for the ...
Plague is of particular concern due to its high risk for human outbreaks, which makes it both a medical and a public health emergency (2–4). Plague is an acute bacterial infection caused by the Gram-negative coccobacillus Yersinia pestis. Although effective antimicrobials are available, this disease has high mortality
Laboratory evidence includes detection by bacterial culture and antigen, antibody, and nucleic acid testing. Antibiotics, including streptomycin and gentamicin, are recommended to effectively treat the different types of plague. Preventive countermeasures include physical isolation of patients, oral antibiotics, and other strategies.
27 maj 2021 · Three key areas selected to be addressed in this guideline: (i) the use of rapid diagnostic tests (RDTs) for diagnosing plague in different contexts; (ii) the choice of antimicrobials for treating the different forms of plague, including whether fluoroquinolones should be introduced as a first-line medicine of choice; and (iii) the use of ...
Before the advent of antibiotics, treatment of plague primarily consisted of supportive care, and fatality rates were high, between 66% and 93%, for all clinical forms (3,13). The development of sulfonamide antibiotics in the 1930s revolutionized the treatment of plague.
26 gru 2017 · Therefore, this minireview briefly introduces the current understanding on Y. pestis and then focuses on practical aspects of plague, including clinical manifestations, diagnosis, treatment, and prevention, to alert clinicians about this notorious disease.
The WHO guidelines on plague surveillance, diagnosis, prevention and control were published in 2009 by the WHO Regional Office for South-East Asia . In 2014, a scientific meeting was convened to revise these guidelines.
