Search results
26 gru 2017 · Therefore, this minireview briefly introduces the current understanding on Y. pestis and then focuses on practical aspects of plague, including clinical manifestations, diagnosis, treatment, and prevention, to alert clinicians about this notorious disease.
25 wrz 2024 · This manual provides comprehensive information on plague epidemiology and recommendations for surveillance, diagnosis, clinical management, and prevention. It also aligns with WHO's proposals from the 75th World Health Assembly to enhance global health emergency preparedness and response.
27 maj 2021 · Three key areas selected to be addressed in this guideline: (i) the use of rapid diagnostic tests (RDTs) for diagnosing plague in different contexts; (ii) the choice of antimicrobials for treating the different forms of plague, including whether fluoroquinolones should be introduced as a first-line medicine of choice; and (iii) the use of ...
Laboratory evidence includes detection by bacterial culture and antigen, antibody, and nucleic acid testing. Antibiotics, including streptomycin and gentamicin, are recommended to effectively treat the different types of plague.
Plague is of particular concern due to its high risk for human outbreaks, which makes it both a medical and a public health emergency (2–4). Plague is an acute bacterial infection caused by the Gram-negative coccobacillus Yersinia pestis. Although effective antimicrobials are available, this disease has high mortality
21 maj 2020 · This systematic review captures aggregate-level antimicrobial treatment and outcome data for patients grouped by antimicrobial treatment regimen and provides data on mortality associated with antimicrobial treatments for plague.
9 paź 2021 · Here, we review research advances in the areas of vaccines and therapeutics for plague in context of Y. pestis virulence factors and disease pathogenesis. Plague continues to be both a public health threat and a biodefense concern and we highlight research that is important for infection mitigation and disease treatment.
