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  1. The LDDST is the screening test of choice for canine hyperadrenocorticism. It is a good screening test for hyperadrenocorticism when the dog has no concurrent medical conditions (eg, diabetes mellitus) or when only dermatological abnormalities are observed.

  2. Life expectancy for dogs with pituitary tumors can vary depending on a number of factors, including the size and location of the tumor, the age and overall health of the dog, and the treatment options that are chosen.

  3. Veterinarians will run routine and specialized blood and urine tests on dogs that have signs of Cushing disease. Retesting may be needed 3 to 6 months later if test results are inconclusive or if the dog does not continue to show signs.

  4. When diagnosing a dog showing symptoms of pituitary disease, veterinarians usually start with a physical exam and diagnostic testing, such as: These tests may show the symptoms are due to a disease not related to the pituitary gland, but if the tests aren’t conclusive, additional testing is necessary.

  5. In dogs, it contains two populations of cells, one of which synthesizes ACTH. A specific population of endocrine cells in the pars distalis (and in the pars intermedia for ACTH in dogs) synthesizes and secretes each of the pituitary tropic hormones.

  6. Diagnosis of pituitary dependent hyperadrenocorticism requires incorporating information from the history, physical examination, and routine laboratory tests. Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs.

  7. Diagnosis of Cushing's disease in dogs requires incorporating information from the history, physical examination, and routine laboratory tests. Canine pituitary dependent hyperadrenocorticism (PDH), also known as Cushing’s disease, is a common endocrine disorder in older dogs.