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Pyrimethamine is classified as a folic acid antagonist. [3] . It works by inhibiting folic acid metabolism and therefore the making of DNA. [3] Pyrimethamine was discovered in 1952 and came into medical use in 1953. [3][5] It is on the World Health Organization's List of Essential Medicines. [6] .
- Pirymetamina
Pirymetamina – organiczny związek chemiczny, środek...
- Pirymetamina
Pirymetamina – organiczny związek chemiczny, środek stosowany w leczeniu malarii, toksoplazmozy, zapalenia płuc wywołanego przez Pneumocystis carinii oraz czerwienicy. Opracowany w 1953 roku przez Gertrudę Elion i George’a Hitchingsa w laboratorium przedsiębiorstwa Wellcome. W 2015 r.
Pyrimethamine is an antiparasitic drug used in the prevention and treatment of toxoplasmosis and malaria. Brand Names. Daraprim. Generic Name. Pyrimethamine. DrugBank Accession Number. DB00205. Background. One of the folic acid antagonists that is used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Pyrimethamine is an aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis.
Kwas folinowy (łac. acidum folinicum) – wielofunkcyjny organiczny związek chemiczny, stosowany jako lek wspomagający w zapobieganiu toksycznemu działaniu antagonistów kwasu foliowego oraz wspomagający działanie 5-fluorouracylu. Historia.
Pyrimethamine (Daraprim) is a diaminopyrimidine that acts as a folic acid antagonist. Its action on Toxoplasma is synergistic with sulfonamides. Pyrimethamine is readily absorbed from the gastrointestinal tract, is lipid-soluble, and is distributed throughout the cells of the body.
Diaminopyrimidines. Pyrimethamine (Daraprim ®) was discovered in 1952 and introduced to the market in 1953. It is a synthetic derivative of ethyl pyrimidine, belonging to the diaminopyrimidines and antimalarials.
