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To understand how proteins function inside cells, one needs to consider the particular physical properties of the intracellular environment and how they shape the cellular behaviors of ordered and intrinsically disordered proteins.
16 gru 2021 · In this review, we first introduced the physicochemical properties of hydrogels and their fabrication approaches concisely. Subsequently, the comprehensive description and deep discussion were...
5 cze 2014 · This work has learned about the unexpected intracellular stability of disordered proteins, their roles in integrating post-translational protein modifications in cell signaling and about their functions in regulatory processes ranging from transcription to cell fate decisions.
28 paź 2020 · We begin with a brief synopsis of the intracellular transport pathways, and subsequently bring into focus the role played by the physicochemical properties, including size, shape, surface chemistry, ligand binding, and mechanical attributes of a variety of nanoparticles, on their intracellular fate. 2.
30 kwi 2020 · We show that the key physicochemical properties of nanoparticles each have a unique role in shaping the translocation outcome, but also have synergistic effects that influence each other.
The cell membrane (or plasma membrane) is a thin closed sheet that fulfils a double role: (a) morphological – delimitates the cell from its external microenvironment and confines all of its subcellular organelles; (b) functional – regulates the exchange...
20 sty 2020 · The underlying physicochemical properties of the biomaterial ultimately regulate the entire cascade of interactions from molecular adsorption and structure to what cells ultimately “feel”.
