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4 sie 2023 · Using cocaine can cause changes to the brain, such as in the reward system, resulting in a buildup of dopamine and making it difficult for someone to stop using the substance. Cocaine can also...
Stimulant Effects Correlate With Brain Activity in Several Areas. Researchers have used functional MRI to obtain detailed information about the roles of different brain areas in producing cocaine-induced euphoria and subsequent craving.
1 wrz 1997 · We investigated brain circuitry mediating cocaine- induced euphoria and craving using functional MRI (fMRI). During double-blind cocaine (0.6 mg/kg) and saline infusions in cocaine-dependent subjects, the entire brain was imaged for 5 min before and 13 min after infusion while subjects rated scales for rush, high, low, and craving.
21 lis 2024 · Both freebase (crack) and powdered cocaine can cause long-term damage to mental health, which appears in the form of mood or emotional disturbances. Because the drug interferes with dopamine re-uptake, long-term use may alter the brain’s ability to regulate dopamine activity.1. Other serious long-term changes to mood and mental health include:2.
18 paź 2024 · The intermediate effects of cocaine on the human brain include changes to the reward system, cognitive impairments, paranoia, hallucinations, risk of stroke, heart attack, low cerebral blood flow, and compulsive drug-seeking behavior.
Cocaine changes how the brain works by increasing the amount of a chemical called dopamine in parts of the brain that control reward and motivation. If you use it often, your brain will get used to the large amount of dopamine produced by the drug, and other healthy activities will seem less interesting or fun.
1 wrz 2013 · We systematically reviewed all available placebo-controlled and case-controlled studies on the acute and long-term effects of cocaine on cognitive functioning. In order to compare the magnitude of cognitive effects across cognitive domains we conducted several meta-analyses on a subset of data from long-term effect studies.
