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After 1 year of TRT, men with prostatic intraepithelial neoplasia (PIN) do not have a greater increase in prostate-specific antigen or a significantly increased risk of cancer than men without PIN.
26 maj 2023 · This review will cover the data relating to commonly used standard-of-care prostate imaging modalities, advances in newer technologies, and newer standards that impact prostate gland imaging.
7 wrz 2020 · Multiple consequences of an external growth stimulus on pre-hyperplastic tissues in the prostate. Inhibition of either the original stimulus, or the secondary messenger growth factors (or hormones) would provide a novel and effective treatment for BPH.
18 mar 2021 · Prostate MRI has seen rapid growth in use in recent years as an advanced diagnostic modality to detect focal areas of clinically significant prostate cancer, to identify an area for targeted biopsy and to guide management and surveillance.
4 kwi 2017 · Under the influence of androgens, the UGE buds into the surrounding UGM and initiates prostate tissue outgrowth. However, although the activation of AR expressed in the UGM is believed to drive UGE specification and differentiation, the molecular mechanisms mediating this inductive process are poorly defined.
16 cze 2020 · This study shows that peri-prostatic adipose tissue can produce chemokines that promote prostate cancer cell migration. Importantly, chemokine-receptor-induced chemotaxis is enhanced by...
Abstract. Advanced-stage prostate cancer (PCa) is often diagnosed with bone metastasis, for which there are limited therapies. Transforming growth factor β (TGF-β) is known to induce epithelial–mesenchymal transition (EMT), and abundance of TGF-β in the bone matrix is one of the important growth factors contributing to bone metastasis.
