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Phototherapy causes little improvement in intrinsic liver function, but pro duces specific changes in bile acid metabolism; these changes may be related to effects of light on a cutaneous bile acid pool.
2 mar 2022 · Sertraline, a selective serotonin reuptake inhibitor, has been shown to be a safe and effective treatment for pruritus in a small randomised placebo‐controlled trial of 12 patients with chronic liver disease. 122 Lastly, the FITCH trial (fibrates for cholestatic ITCH) demonstrated the effectiveness of bezafibrate, a peroxisome proliferator ...
Key point. Patients with liver disease often have various complex acid-base disorders. Pathophysiological and diagnostic concepts as well as potential therapeutic interventions are reviewed in this article.
The term acute liver failure (ALF) is frequently applied as a generic expression to describe patients presenting with or developing an acute episode of liver dysfunction. It is characterised by a deterioration in liver function tests, and potentially associated with dysfunction in other organs.
15 lis 2018 · At the end of the last century, some artificial liver devices began to develop with the aim of being used as supportive therapy until liver transplantation (bridge-to-transplant) or liver regeneration (bridge-to-recovery).
1 wrz 2024 · Proper identification, prevention and treatment of complications such as intracranial hypertension and sepsis are critical to optimising outcomes. The identification of the cause of acute liver failure and the prompt initiation of the aetiological treatment can also improve prognosis.
15 gru 2023 · Acute-on-chronic liver failure (ACLF) occurs in patients with scarring of the liver, who sustain a further injury. This condition carries a high mortality rate with no definitive treatments beyond liver transplantation. Here, we discuss the mechanisms that govern ACLF, which can be targeted for treatment.
