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  1. Peripheral artery disease (PAD) is a vascular disorder that causes abnormal narrowing of arteries other than those that supply the heart or brain. [5] [15] PAD can happen in any blood vessel, but it is more common in the legs than the arms. [16]

  2. 11 gru 2020 · Lower limb peripheral arterial disease (or peripheral arterial disease for short) is a marker for increased risk of cardiovascular events even when it is asymptomatic. The most common initial symptom of peripheral arterial disease is leg pain while walking, known as intermittent claudication.

  3. 8 kwi 2024 · Lower extremity peripheral artery disease (PAD) affects between 116 and 230 million people worldwide. 1 Manifestations of PAD range from asymptomatic, in which patients report no exertional leg symptoms, to chronic limb-threatening ischemia (CLTI), defined by lower-limb rest pain, gangrene, or ulceration. 2 Compared with age-matched people ...

  4. 26 sie 2017 · 2017 ESC Guidelines on the Diagnosis and Treatment of Peripheral Arterial Diseases, in collaboration with the European Society for Vascular Surgery (ESVS): Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries

  5. 22 maj 2024 · In this brief Centennial Collection overview, we begin by summarizing the known and emerging mechanisms underlying PAD (Figure) and then highlight novel translational therapies that promise to improve outcomes for those experiencing this highly morbid condition. Figure. Mechanisms contributing to PAD.

  6. Peripheral artery disease is a growing public health problem. We aimed to estimate the global disease burden of peripheral artery disease, its risk factors, and temporospatial trends to inform policy and public measures. Methods.

  7. 5 paź 2023 · Peripheral arterial disease (PAD) is most commonly caused by atherosclerosis. Most patients are asymptomatic. Patients require aggressive risk factor control. Long-term patency of lower-extremity revascularisation should be monitored with a surveillance programme.

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