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1 lip 2024 · Peripheral artery disease (PAD) stands as one of the most prevalent cardiovascular diseases (CVDs). Its pathogenesis involves atherosclerotic narrowing of arteries, leading to inadequate blood flow and subsequent ischemia. Diagnosis of PAD typically relies on clinical symptoms and a reduced ankle-brachial index (ABI).
Peripheral artery disease (PAD) is a global problem that has been estimated to affect more than 200 million people worldwide with increasing disease incidence (Fowkes et al. 2013).
A variety of putative mediating pathophysiologic mechanisms were measured including the reactivity to MS of blood pressure, heart rate, catecholamines, inflammatory markers, and peripheral arterial tone; myocardial ischemia using Holter monitoring, and ventriculography; echocardiographic changes related to ischemia and diastology; functional ...
Peripheral artery disease (PAD) is a highly prevalent condition affecting 8.5 million people in the United States alone [1]. PAD patients experience debilitating symptoms such as intermittent claudication and complications that can lead to undesirable outcomes, including amputation.
28 kwi 2020 · Psychosocial factors and cardiovascular health are closely tied. As such, it is important to recognize psychosocial factors and these associations as we work to prevent CVD, treat patients with known disease, and improve both psychosocial well‐being and cardiovascular health for all.
25 wrz 2019 · This study shows that greater peripheral microvascular constriction during acute psychological stress, mediated at least partly by β-sympathetic nervous system activation, independently predicts adverse cardiovascular events in subjects with stable coronary artery disease.
22 maj 2024 · In this brief Centennial Collection overview, we begin by summarizing the known and emerging mechanisms underlying PAD (Figure) and then highlight novel translational therapies that promise to improve outcomes for those experiencing this highly morbid condition. Figure. Mechanisms contributing to PAD.
