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Learn about the veterinary topic of Use of Penicillins in Animals. Find specific details on this topic and related topics from the MSD Vet Manual.
The major MOAs of antimicrobial agents, with examples of each type, are as follows (also see Antibacterial Agents): Inhibition of cell wall synthesis: beta-lactams (penicillins, cephalosporins, and cephamycins), glycopeptides (vancomycin), bacitracin, fosfomycin.
Examples of applications in veterinary medicine: Erythromycin: drug of choice against Campylobacter jejuni. Can be an alternative to penicillin in penicillin-allergic animals and second choice for anaerobic infections. Tylosin and spiramycin: used against Mycoplasma infections; used as growth promotants.
Animal Research. Areas of research. Research by disease. Penicillin. Florey and Chain first tested the effects of penicillin in mice in 1940. By 1941, penicillin was being used to treat dying soldiers. This research won the Nobel Prize in 1945.
8 lut 2018 · Some β-lactamases are specific for penicillins (penicillinases), some are specific for cephalosporins (cephalosporinases), and others have affinity for both groups. The genes that code for β-lactamases can occur via mutations in chromosomes, or they may be transferred by genetic elements.
There are many different classes of antibiotics available for use in animals, including penicillins, cephalosporins, cephamycins, aminoglycosides, quinolones, sulfonamides, tetracyclines, and macrolides.
In cattle, pigs, and poultry, the oral route of administration is the most widely used. Formulations range from premixes and drinking-water additives to licks, pastes, drenches, tablets, capsules, and boluses. Oral dosage forms are usually intended for systemic effects resulting from drug absorption from the GI tract.
