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14 paź 2024 · Approximately, 10% of people report a penicillin allergy; however, more than 90% can safely undergo delabeling after a detailed history, oral challenge, or other investigations such as penicillin skin testing (PST).
In the United States, patients commonly report having a penicillin allergy, with penicillin being the most frequent beta-lactam allergy. However, very few patients experience a clinically significant immune-mediated allergic reaction to penicillin.
16 wrz 2024 · This systematic review and meta-analysis found that reactions to direct penicillin challenges may be infrequent across a variety of patient populations and protocols, suggesting that penicillin challenges may be safe for incorporation into routine penicillin allergy delabeling efforts.
11 sty 2023 · People who have a suspected penicillin (or closely related antibiotic) allergy and require penicillin to treat a life-threatening condition for which no alternate antibiotic is appropriate (eg, syphilis).
4 sie 2017 · Here, we discuss key features that help to distinguish patients at low or high risk of having a true penicillin allergy, summarise what is known about the risk of allergic reactions to other β lactam antibacterials in patients with penicillin allergy, and discuss the steps to consider when assessing a label of penicillin allergy.
15 sty 2019 · More than 95% of patients labeled as having a penicillin allergy ultimately are able to tolerate this class of drugs. 8 Most patients labeled with penicillin allergy do not undergo any evaluation to determine the accuracy or persistence of the allergy. 9,10 This review summarizes the epidemiology of, clinical consequences of, and methods for ...
11 cze 2021 · PCPs discussions with patients about their penicillin allergy might be beneficial, with a particular focus on the difference between a side effect and allergic reactions. This knowledge might also increase patient and PCP motivation to engage with the process of delabelling.
