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23 maj 2022 · This article reviews our evolving understanding of penicillin hypersensitivity at the 80th anniversary of penicillin’s clinical introduction. Penicillin breakdown products covalently bond to serum proteins, leading to classic drug hypersensitivity. Penicillin remains the most frequently reported drug “allergy.”.
This paper provides a review of the modes of action, spectrums of activity, adverse effects for the various classes of penicillin most often used in primary care and highlights clinical issues in managing women with penicillin allergy.
15 sty 2019 · This narrative review summarizes the epidemiology of penicillin allergy and the clinical consequences of misattributing adverse drug events to β-lactam
Abstract. Antimicrobials in the penicillin class are first line treatments for several infectious diseases in the pediatric and adult population today. In the United States, patients commonly report having a penicillin allergy, with penicillin being the most frequent beta-lactam allergy.
10 lip 2024 · Recent developments include national guidelines for non-allergist delivered PADL and validation of penicillin allergy risk assessment tools.
21 paź 2019 · The summarized results of this review provide good evidence that most adult patients reporting penicillin allergy, when determined to be low risk for anaphylaxis, tolerate repeat penicillin administration without any adverse reactions.
15 sty 2019 · Evaluation of penicillin allergy before deciding not to use penicillin or other β-lactam antibiotics is an important tool for antimicrobial stewardship. Many patients report they are allergic to penicillin but few have clinically significant reactions.
