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The most commonly reported drug class allergy is to penicillins, with penicillin being the most common beta-lactam allergy [1, 2]. Approximately 8–10% of people in the United States report a penicillin allergy [2, 3]. Hypersensitivity reactions are common with penicillins [4].
4 paź 2024 · Penicillin antibiotics are a first-line treatment for many peripartum infections, including intra-amniotic infections and group B Streptococcus prophylaxis. 1 Pregnant patients who receive non–penicillin antibiotics have higher rates of morbidity, health care utilization, and adverse drug reactions. 2-4 More than 90% of patients who carry a peni...
14 lut 2020 · Twenty-seven studies were assessed by bivariate meta-analysis. Skin tests had a summary sensitivity of 30.7% (95% CI, 18.9%-45.9%) and a specificity of 96.8% (95% CI, 94.2%-98.3%), with a partial area under the summary receiver-operating characteristic curve of 0.686 (I2 = 38.2%).
4 sie 2017 · Here, we discuss key features that help to distinguish patients at low or high risk of having a true penicillin allergy, summarise what is known about the risk of allergic reactions to other β lactam antibacterials in patients with penicillin allergy, and discuss the steps to consider when assessing a label of penicillin allergy.
SUMMARY. Penicillin allergies are not always lifelong. Approximately 50% are lost over five years. A reaction to penicillin during a childhood infection is unlikely to be a true allergy. Only 1–2% of patients with a confirmed penicillin allergy have an allergy to cephalosporins.
11 gru 2019 · Penicillin is the most common drug allergy identified in medical records, with a prevalence ranging from 6 to 25% across various regions and treatment populations. 5,6 Benign cutaneous reactions...
This guideline addresses immediate and non-immediate allergic reactions to beta-lactams. Up to 20% of drug-related anaphylaxis deaths in Europe and up to 75% in the United States are caused by penicillin. (C) Repeated courses are more sensitizing than a single prolonged course.
