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15 sty 2019 · A decision model to project clinical outcomes for patients with methicillin-susceptible S aureus bacteremia and reported penicillin allergy found that risk stratification based on allergy history resulted in fewer treatment failures and deaths compared with prescribing an alternative antibiotic. 44 Another study reported that including more ...
Clindamycin serves as an alternative surgical prophylactic antibiotic in patients with penicillin (PCN) or cephalosporin allergy labels. In the previous reports, the use of clindamycin was associated with higher incidences of surgical site infections (SSIs).
Patients with only a penicillin allergy documented receive alternative antibiotics that are more broad-spectrum and have lower efficacy or increased side-effects, such as vancomycin, clindamycin, gentamicin, and fluoroquinolones. 47 Alternatives are used even when β-lactams are indicated. 74,75 Canadian inpatients with a β-lactam allergy ...
13 maj 2024 · This topic will present an approach to determining whether a patient with reported penicillin allergy can be treated with penicillins or related beta-lactam antibiotics, with or without access to allergy consultation.
2 sty 2018 · Commonly used alternatives to penicillin, such as vancomycin, clindamycin, and fluoroquinolones, are clearly associated with the development of resistant organisms such as vancomycin-resistant Enterococcus and increased rates of Clostridium difficile.
15 sty 2019 · Evaluation of penicillin allergy before deciding not to use penicillin or other β-lactam antibiotics is an important tool for antimicrobial stewardship. Many patients report they are allergic to penicillin but few have clinically significant reactions.
19 sie 2024 · Not all bacterial infections are treated with penicillin, but if you have an infection that is usually treated by penicillin, you may be able to take a drug that is similar to penicillin called a cephalosporin. Over 95 percent of people with penicillin allergy can safely take cephalosporins, which are a bit structurally different from penicillins.