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Clindamycin serves as an alternative surgical prophylactic antibiotic in patients with penicillin (PCN) or cephalosporin allergy labels. In the previous reports, the use of clindamycin was associated with higher incidences of surgical site infections (SSIs).
13 maj 2024 · This topic will present an approach to determining whether a patient with reported penicillin allergy can be treated with penicillins or related beta-lactam antibiotics, with or without access to allergy consultation.
Avoid cephalosporins and other Beta-lactams in the treatment of mild-moderate infection in Type 1 allergy when alternative agents are available (penicillin allergy options on all antimicrobial guidelines) Introduction.
15 sty 2019 · A decision model to project clinical outcomes for patients with methicillin-susceptible S aureus bacteremia and reported penicillin allergy found that risk stratification based on allergy history resulted in fewer treatment failures and deaths compared with prescribing an alternative antibiotic. 44 Another study reported that including more ...
2 sty 2018 · Commonly used alternatives to penicillin, such as vancomycin, clindamycin, and fluoroquinolones, are clearly associated with the development of resistant organisms such as vancomycin-resistant Enterococcus and increased rates of Clostridium difficile.
Penicillin allergies are reported by 8–15% of the US population, but up to 95% of these allergies do not correspond with a true allergy when tested. ... % increased odds of SSI among patients reporting a penicillin allergy entirely attributable to the use of a beta-lactam alternative antibiotic (primarily clindamycin or vancomycin). 3 In ...
As expected, second line antibiotics, such as fluoroquinolones, clindamycin, and vancomycin, were more commonly utilized in cases. Similar results were reported in a retrospective chart review study [39] presented as an abstract at the American Academy of Allergy, Asthma and Immunology.
