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  1. Clindamycin serves as an alternative surgical prophylactic antibiotic in patients with penicillin (PCN) or cephalosporin allergy labels. In the previous reports, the use of clindamycin was associated with higher incidences of surgical site infections (SSIs).

  2. Alternative antibiotic options to use in penicillin allergic patients to treat specific infections are included in all sections of this antibiotic website. References

  3. 13 maj 2024 · This topic will present an approach to determining whether a patient with reported penicillin allergy can be treated with penicillins or related beta-lactam antibiotics, with or without access to allergy consultation.

  4. Penicillin allergies are reported by 8–15% of the US population, but up to 95% of these allergies do not correspond with a true allergy when tested. ... % increased odds of SSI among patients reporting a penicillin allergy entirely attributable to the use of a beta-lactam alternative antibiotic (primarily clindamycin or vancomycin). 3 In ...

  5. Patient-reported penicillin allergies alter antibiotic management and may result in the use of suboptimal or broader spectrum drugs such as fluoroquinolones, macrolides, glycopeptides and cephalosporins. 6, 8 - 11 Having a penicillin allergy label has been associated with an increased risk of Clostridium difficile, methicillin-resistant Staphylo...

  6. 15 sty 2019 · The consequences of being labeled as having a penicillin allergy include the use of alternative antibiotics that cause more treatment failures and adverse effects than β-lactams and contribute to antimicrobial resistance development.

  7. 11 sty 2023 · People who have a suspected penicillin (or closely related antibiotic) allergy and require penicillin to treat a life-threatening condition for which no alternate antibiotic is appropriate (eg, syphilis).

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