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  1. consensus includes intravenous CD20 inhibitors as a first-line therapy option for moderate-to-severe pemphigus. (J Am Acad Dermatol 2020;82:575-85.) Key words: CD20 inhibitor; consensus; guidelines; pemphigus foliaceus; pemphigus vulgaris; treatment. Pemphigus encompasses a spectrum of rare mucocu-taneous bullous diseases that are autoimmune ...

  2. These recommendations are a working document whose purpose is to provide clinicians with the most up-to-date consensus on the diagnosis and management of pemphigus. Further studies are needed to clarify optimal therapeutic regimens and describe their safety and efficacy in the treatment of pemphigus.

  3. Abstract. Background: Several European countries recently developed international diagnostic and management guidelines for pemphigus, which have been instrumental in the standardization of pemphigus management. Objective: We now present results from a subsequent Delphi consensus to broaden the generalizability of the recommendations.

  4. Fig 2 Treatment options. The principal objective is to promote the healing of blisters and erosions, prevent development of new lesions, and minimize serious side effects of treatment.

  5. This international consensus includes intravenous CD20 inhibitors as a first-line therapy option for moderate-to-severe pemphigus. We present here the recommendations resulting from this Delphi process.

  6. Objectives: Review the pathophysiology of pemphigus foliaceus. Describe the typical presentation of pemphigus foliaceus. Outline the treatment options for pemphigus foliaceus. Explain the importance of improving care coordination amongst interprofessional team members to optimize outcomes for patients affected by pemphigus foliaceus.

  7. 31 sty 2023 · Systemic corticosteroids represent the first-line treatment in all forms of pemphigus. 7 Adjuvant medications include azathioprine and mycophenolate compounds. 7 Rituximab, an anti-CD20 monoclonal antibody that induces B-cell depletion, has been shown to improve patient survival. 8 Currently, rituximab in conjunction with corticosteroids is firs...