Search results
23 wrz 2021 · Peak and trough levels indicate drug levels in an individual’s body. A peak is the highest level of a medication in the blood, while a trough level indicates the lowest concentration. Troughs of medication concentration occur after the drug has been broken down and metabolized by the body.
- Therapeutic Index
"Katzung & Trevor's Pharmacology Examination and Board...
- Lithium
Past medical history is significant for bipolar disorder and...
- Therapeutic Index
peak level. Therapeutics The highest serum level of free or unbound drug in a Pt based on a dosing schedule, which is usually measured ± 1 ⁄ 2 hr after an oral dose of a drug. See Therapeutic drug monitoring. Cf Trough level.
Cmax is the maximum (or peak) serum concentration that a drug achieves in a specified compartment or test area of the body after the drug has been administered and before the administration of a second dose. [1] It is a standard measurement in pharmacokinetics.
A trough level is contrasted with a "peak level" (Cmax), which is the highest level of the medicine in the body, and the "average level", which is the mean level over time. It is widely used in clinical trials for newer medicines to investigate therapeutic effectiveness and safety.
A peak drug level is drawn after the medication is administered and is known to be at the highest level in the bloodstream. A trough level is drawn when the drug is at its lowest in the bloodstream, right before the next scheduled dose is given.
The peak is the highest concentration that a medication can achieve in the blood. When drawing a peak level, it is helpful for the examiner to note the time it took to achieve this maximum concentration. This is important when measuring toxicity levels.
Peak refers to the highest concentration of a drug in the bloodstream after administration. It indicates the point at which the medication is most effective.
