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1 sty 2023 · Extraordinary efforts led to important advances in virology, immunology and pathophysiology, and therapeutics that changed the paradigm of HIV management.
Host HLA genetics and HIV diversity: frequent transmission of escaped epitopes and epitope loss over time
Breakthroughs in the prevention of HIV important to public health include male medical circumcision, antiretrovirals to prevent mother-to-child transmission, antiretroviral therapy in people with HIV to prevent transmission, and antiretrovirals for pre-exposure prophylaxis.
1 sty 2023 · HIV infection induces a humoral response to virtually all of HIV’s regulatory and structural proteins, including Env antibodies, matrix proteins, viral nucleocapsid proteins, and virus regulatory proteins.
This document provides an overview of the pathophysiology of HIV/AIDS. It begins by outlining predisposing and precipitating factors that can increase risk of HIV infection like age, lifestyle, sexual behaviors, and occupations.
Dokumen tersebut menjelaskan tentang patofisiologi penularan HIV, dimana virus HIV masuk ke dalam tubuh melalui cairan darah, cairan sperma, cairan vagina, atau ASI lalu melekat pada sel CD4 dan mereplikasi diri dengan cara mengintegrasikan DNA ke dalam sel inang.
In ARV-naïve subjects chronically infected with a “wild-type” HIV-1 • All non-deletereous single mutants likely preexist • Few double mutants preexist • Almost no triple mutants are expected
