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HIV is the greatest escapist. HIV-1 Strategies to counteract host immunity. Adaptive immunity. Intrinsic immunity. HUGE GENETIC DIVERSITY. Population level. Individual level. Deep sequencing. Sanger sequencing. Balance between mutation rate, drift and selection. High replication rate: 109-12 new virions/day. Error-prone polymerase:
1 sty 2023 · Pathophysiology of HIV and strategies. PDF | Since its discovery, it is estimated that human immunodeficiency virus (HIV) has infected more than 80 million people and caused more than 36......
Breakthroughs in the prevention of HIV important to public health include male medical circumcision, antiretrovirals to prevent mother-to-child transmission, antiretroviral therapy in people with HIV to prevent transmission, and antiretrovirals for pre-exposure prophylaxis.
Host HLA genetics and HIV diversity: frequent transmission of escaped epitopes and epitope loss over time
1 sty 2023 · HIV infection induces a humoral response to virtually all of HIV’s regulatory and structural proteins, including Env antibodies, matrix proteins, viral nucleocapsid proteins, and virus regulatory proteins.
