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1 lip 2005 · Nontoxic and toxic multinodular goiter are the main etiologies of goiter in patients aged 55 years and older. Thyroid size is the main factor influencing the appearance of signs and symptoms, although age and sex are related with the presence of retrosternal goiter and tracheal deviation.
Nodular goiter is caused by hyperplasia of follicular cells in one or more areas of the thyroid gland. The basic goitrogenic process is the development of new follicular cells with abnormal growth potential that form new follicles or the increase in size of newly formed follicles.
14 sie 2023 · Pathophysiology of Nodular Goiter. Diffuse nontoxic goiter is considered to be the precursor of euthyroid thyroid nodules and nontoxic multinodular goiter. So the pathophysiology of diffuse nontoxic goiter also applies to nodular goiter. In addition, the following mechanisms can be considered:
The risk factors for goiter include intrinsic biological factors (which account for the five- to tenfold higher prevalence of goiter among women) as well as cigarette smoking, naturally occurring goitrogens, selenium or zinc deficiency, and emotional stress.
17 cze 2014 · Nodular goiter is the most common pathology of the thyroid gland. Palpable thyroid nodules are found in 3-7% of adult population and are more frequent in women. Ultrasonography which has been introduced in the diagnosis of thyroid gland has confirmed earlier autopsy reports indicating that focal lesions are found in as many as 50% of clinically ...
9 mar 2017 · Nontoxic goiter is a common condition related to deficiency in the iodine intake. Other etiological factors include genetic susceptibility, female gender, age, and tobacco smoking. Since the thyroid tissue has preponderance for nodular degeneration, most goiters...
15 lip 2024 · The past few years have witnessed an increasing incidence of nodular goiter (NG), with a well-documented higher prevalence in females than males. This gender disparity has led research to focus primarily on female subjects, potentially overlooking common pathogenic mechanisms in both sexes.
