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1 lip 2020 · Virulence factors of pathogenic E. coli can affect a wide range of eukaryotic cellular processes, including cell signalling, ion secretion, protein synthesis, mitosis, cytoskeletal function and mitochondrial function. Bacterial infections are usually treated with antibiotics.
13 lip 2023 · In general, extraintestinal infections caused by E. coli are susceptible to a variety of antibiotics, as listed below. E. coli can harbor genes for antibiotic resistance, and antibiotic therapy targeting these organisms must be tailored.
24 cze 2024 · When E. coli strains acquire certain additional genetic material, they can become pathogenic; these pathogenic clones circulate widely and are among the most virulent enteric pathogens. Diarrheagenic E. coli are among the most frequent bacterial causes of gastroenteritis worldwide.
25 sty 2021 · Recently, a new pathotype called adherent-invasive E. coli (AIEC) has been proposed as being associated with inflammatory bowel disease, especially Crohn’s disease. As Gram-negative organisms, E. coli are resistant to many antibiotics, and high-risk E. coli multiresistant clones are emerging.
The evolution of pathogenic E. coli that has resulted in formation of distinct pathotypes capable of colonizing the gastrointestinal tract, urinary tract or meninges illustrates how key...
Although Escherichia coli can be an innocuous resident of the gastrointestinal tract, it also has the pathogenic capacity to cause significant diarrheal and extraintestinal diseases. Pathogenic variants of E. coli (pathovars or pathotypes) cause much morbidity and mortality worldwide.
Here, we briefly revisited the details of these E. coli classic and hybrid pathogens, the increase in antimicrobial resistance in the context of a genetically empowered multifaceted and versatile bug and the growing need to advance alternative therapies to fight these infections.
