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15 cze 2022 · Parvovirus B19 is a small, non-enveloped, single-stranded DNA virus with global distribution. It is primarily known for being the causative agent of fifth disease, also known as erythema infectiosum, a common self-limiting childhood disease characterized by the development of a rash.
Parvovirus B19 (B19) was discovered serendipitously in 1974 and is the only member of the family Parvoviridae known to be pathogenic in humans. The virus is widespread, and manifestations of infection vary with the immunologic and hematologic status of the host.
1 sty 2023 · Parvovirus B19 (B19V) is a small ssDNA non-enveloped virus, member of Parvoviridae family. The infection is widely diffused and is responsible for a broad range of clinical manifestations including fifth disease in children, transient aplastic crisis in patients with haematological disorders, non-immune hydrops fetalis in pregnant women ...
10 paź 2024 · Exploring Parvovirus B19 involves examining its structural components, transmission routes, cellular entry mechanisms, host immune response, diagnostic methods, and ongoing research. Each area offers insights into managing and mitigating the effects of this virus.
Our structural and functional understanding of parvovirus capsids and their ligands has increased as imaging and molecular techniques have advanced, and capsid structures for most groups within the Parvoviridae family have now been determined.
1 lis 2021 · Structure of the human parvovirus B19 genome and the human parvovirus B19 genetic map. Open in a new tab (A) Schematic diagram of the minus strand of the B19V ssDNA genome.
17 kwi 2019 · We have determined and report here the high-resolution structure of B19 virus-like particles (VLPs) complexed with the Fab of a human neutralizing antibody. The structure shows a quaternary structure epitope formed by three VP2 proteins and provides details on host recognition of human B19 virus.
