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9 kwi 2024 · Bone ossification is the formation of new bone, which can occur in two ways: intramembranous ossification and endochondral ossification. This article will discuss both forms as well as clinically relevant examples.
Ossification. Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling. Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts.
The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the long bones form via endochondral ossification.
Ossification occurs toward both ends of the bone from the primary ossification center, and it eventually forms the shaft of the bone in the case of long bones. Secondary ossification centers form after birth. Ossification from secondary centers eventually forms the ends of the bones.
30 paź 2023 · Bone matrix secreted by the osteoblasts forms a bone collar. The bone collar prevents nutrients from reaching the hypertrophied chondrocytes, causing them to degenerate. Osteoclasts, cells that break down bone, arrive and form holes in the bone collar allowing the passage of periosteal buds.
19 sie 2021 · Bone, or osseous tissue, is a connective tissue that constitutes the endoskeleton. It contains specialized cells and a matrix of mineral salts and collagen fibers. The mineral salts primarily include hydroxyapatite, a mineral formed from calcium phosphate.
Definition. Ossification is the process by which bone tissue is formed, allowing for the development and growth of bones in the body. This biological process transforms cartilage or fibrous tissues into bone, playing a crucial role in skeletal system development and fracture healing.
