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Ossification. Bone is broken down by osteoclasts, and rebuilt by osteoblasts, both of which communicate through cytokine (TGF-β, IGF) signalling. Ossification (also called osteogenesis or bone mineralization) in bone remodeling is the process of laying down new bone material by cells named osteoblasts.
9 kwi 2024 · Bone ossification is the formation of new bone, which can occur in two ways: intramembranous ossification and endochondral ossification. This article will discuss both forms as well as clinically relevant examples.
Bone formation, process by which new bone is produced. Ossification begins about the third month of fetal life in humans and is completed by late adolescence. The process takes two general forms, one for compact bone and the other for cancellous bone.
Ossification occurs toward both ends of the bone from the primary ossification center, and it eventually forms the shaft of the bone in the case of long bones. Secondary ossification centers form after birth.
The direct conversion of mesenchymal tissue into bone is called intramembranous ossification. This process occurs primarily in the bones of the skull. In other cases, the mesenchymal cells differentiate into cartilage, and this cartilage is later replaced by bone.
30 paź 2023 · Bone formation in a developing embryo begins in mesenchyme and occurs through one of two processes: either endochondral or intramembranous osteogenesis (ossification). Intramembranous ossification is characterized by the formation of bone tissue directly from mesenchyme.
15 cze 2023 · Ossification, also known as osteogenesis or bone formation, is the process by which bone tissue is created. It begins during embryonic development and continues until early adulthood, with slight individual variations. There are two types of ossification: intramembranous and endochondral.
