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  1. CLASSIFICATION. USE. DOSE (for cats and dogs unless otherwise noted) Chlorpromazine. Alpha-2 adrenergic antagonist D2 dopaminergic antagonist H1 histaminergic antagonist M1 muscarinic cholinergic antagonist. Antiemetic. 0.2–0.4 mg/kg SC or IM Q 8 H. Cisapride. 5-HT4 serotonergic agonist.

  2. If your cat is hard to pill, consider the injectable forms of the nausea meds, which are often much easier to give than oral. (Injectable Cerenia does sting most cats, but less so if kept refrigerated.) For ondansetron (not Cerenia), the injectable also needs to be given less often than oral. ONDANSETRON (ZOFRAN) Suggested Oral Ondansetron Dosage

  3. 1 mar 2010 · Ondansetron is available as a 2 mg/ml injectable, 4 mg tablets and an oral solution (4 mg per 5 ml). The empirical dosage in cats is 0.5 mg/kg bid. Dolasetron is supplied as an injectable and as 50 mg tablets, which must be reformulated for use in cats. The empirical dosage is 0.6–1.0 mg/kg IV or PO sid.

  4. Ondansetron (brand names Zofran®, Zuplenz®) is an antiemetic used off label (extra label) to treat severe nausea and vomiting in dogs and cats. Many drugs are commonly prescribed for off-label use in veterinary medicine.

  5. Ondansetron is used to treat and/or prevent severe vomiting in dogs and cats. The FDA (U.S. Food & Drug Administration) has approved this drug for use in humans, but it is not officially approved for use in animals.

  6. Six cats with normal complete blood count, serum biochemistry, and urinalysis received 2 mg oral (mean 0.43 mg/kg), subcutaneous (mean 0.4 mg/kg), and intravenous (mean 0.4 mg/kg) ondansetron in a cross-over manner with a 5-day wash out.

  7. Dogs and cats. Indications for use, specifying the target species Symptomatic treatment of vomiting and reduced gastro-intestinal motility associated with gastritis, pyloric spasm, chronic nephritis and digestive intolerance to some drugs.

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