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Ondansetron (brand names Zofran®, Zuplenz®) is an antiemetic used off label (extra label) to treat severe nausea and vomiting in dogs and cats. Many drugs are commonly prescribed for off-label use in veterinary medicine.
CLASSIFICATION. USE. DOSE (for cats and dogs unless otherwise noted) Chlorpromazine. Alpha-2 adrenergic antagonist D2 dopaminergic antagonist H1 histaminergic antagonist M1 muscarinic cholinergic antagonist. Antiemetic. 0.2–0.4 mg/kg SC or IM Q 8 H. Cisapride. 5-HT4 serotonergic agonist.
22 lip 2022 · The intravenous dose is 0.05 to 0.1 mg per pound (0.1 to 0.2 mg/kg). In cats, the usual dose is 0.11 mg per pound (0.22 mg/kg) every 8 to 12 hours. Ondansetron is a common medication that can be used to treat vomiting in dogs and cats. Read this article to learn more about dosage and side effects.
For acute vomiting: 2 mg/kg, PO, or 1 mg/kg, SC, q 24 h (acute vomiting); 8 mg/kg/day, PO, for up to 2 days (motion sickness) For motion sickness: 8 mg/kg, PO, q 24 h for up to 2 d. *Dogs with ABCB1 polymorphism may be predisposed to adverse events. In these topics.
1 mar 2010 · Omeprazole is available in 10 and 20 mg capsules. An empirical dosage in cats (and dogs) is 0.5–1.0 mg/kg PO sid. The drug is enteric-coated to prevent degradation. If reformulated, enteric-coated granules can be measured and placed in a gelatin capsule.
8 lut 2018 · The doses used for ondansetron are 0.5–1.0 mg/kg, IV or oral 30 minutes prior to administration of cancer drugs. For other diseases it has been administered at a dose of 0.1–0.2 mg/kg to dogs and cats and increased to 0.5 mg/kg if necessary, and given as often as every 12 hours.
Ondansetron is most often used in dogs and cats undergoing chemotherapy, to stop the vomiting caused by anti-cancer drugs. It is given to veterinary patients when other drugs have not controlled severe vomiting or when patients are unable to tolerate the more commonly prescribed anti-emetics.