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1 mar 2010 · Omeprazole is available in 10 and 20 mg capsules. An empirical dosage in cats (and dogs) is 0.5–1.0 mg/kg PO sid. The drug is enteric-coated to prevent degradation. If reformulated, enteric-coated granules can be measured and placed in a gelatin capsule.
ondansetron is poorly absorbed in cats (32%, vs. 62% in humans and 10% in dogs), and has a short duration of action in them (approx. 1 to 3 hours, vs. approx. 3 to 6 hours in humans). SubQ duration
CLASSIFICATION. USE. DOSE (for cats and dogs unless otherwise noted) Chlorpromazine. Alpha-2 adrenergic antagonist D2 dopaminergic antagonist H1 histaminergic antagonist M1 muscarinic cholinergic antagonist. Antiemetic. 0.2–0.4 mg/kg SC or IM Q 8 H. Cisapride. 5-HT4 serotonergic agonist.
Prediction of ondansetron in cat serum following dosing at 0.5 and 1 mg/kg via i.v., oral and SQ dosing utilizing varied dosing intervals was carried out using nonparametric superposition based on concentration data from single dose studies for each individual cat.
1 lis 2009 · Ondansetron (0.1-0.2 mg/kg q 6-12 h as a slow IV injection or for chemotherapy 0.5 mg/kg IV) is the prototypical drug in the class and is now a viable choice in veterinary medicine due to the low cost of generics. Granisetron and dolasetron are also in the same drug class but are costly. Ondansetron is primarily eliminated by hepatic metabolism.
Dolasetron. 0.6–1 mg/kg, IV, q 24 h. Maropitant. For acute vomiting: 2 mg/kg, PO, or 1 mg/kg, SC, q 24 h (acute vomiting); 8 mg/kg/day, PO, for up to 2 days (motion sickness) For motion sickness: 8 mg/kg, PO, q 24 h for up to 2 d. *Dogs with ABCB1 polymorphism may be predisposed to adverse events. In these topics.
Ondansetron (brand names Zofran®, Zuplenz®) is an antiemetic used off label (extra label) to treat severe nausea and vomiting in dogs and cats. Many drugs are commonly prescribed for off-label use in veterinary medicine.
