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NT-proBNP calculator cannot and will not be held legally, financially, or medically responsible for calculated NT-proBNP values and decisions made based on the NT-proBNP values obtained using this auto-calculation tool.
13 wrz 2022 · In males, median (97.5th centile) NT-proBNP concentration at age <30 years was 21 (104) pg/mL, rising to 38 (195) pg/mL at 50 to 59 years, and 281 (6792) pg/mL at ≥80 years. In females, median NT-proBNP at age <30 years was 51 (196) pg/mL, 66 (299) pg/mL at 50 to 59 years, and 240 (2704) pg/mL at ≥80 years ( Table 1 ).
The reference range for NT-proBNP varies depending on the nature of the control population. The NT-proBNP values are related to, for example, age and body mass index (BMI). It should be noted that only few data are available on healthy subjects in whom cardiac dysfunction was ruled out by echocardiography [2].
23 kwi 2023 · Like BNP, NT-proBNP concentrations vary by age; the normal threshold for those under 50 years of age is 450 pg/mL, while it is 900 pg/mL for those greater than 50 years of age. The clinical importance of measuring one peptide over the other has not yet been demonstrated.
18 wrz 2023 · NT-proBNP values below 300 pg/mL have a 99% negative predictive value for excluding acute CHF. A cutoff of 1200 pg/mL for patients with an eGFR below 60 yields a diagnostic sensitivity and specificity of 89% and 72% for acute CHF.
Normal levels. BNP < 100 pg/ml (29 pmol/litre) or NTproBNP < 400 pg/ml (47 pmol/litre) Notes: serum natriuretic peptides: obesity or treatment with diuretics, angiotensin-converting enzyme (ACE) inhibitors, beta-blockers, angiotensin II receptor antagonists (ARBs) and aldosterone antagonists can reduce levels of serum natriuretic peptides
NT-proBNP compares favorably with the high-quality data from ICON-RELOADED, where the gray zone was 300 to 1,800 pg/ml, or 3-fold the FDA normal range for age >75 years. Figure 1. Comparison of NT-proBNP Cutpoints.
