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LDL-P • LDL-P is the direct measure of low density lipoprotein particles - the causal link between high levels of LDL-P and development of cardiovascular disease (CVD) is well established. • Studies have demonstrated per-particle cholesterol amount varies in patients with type II diabetes, statin-treated
LDL can be directly measured by LDL particle number (ApoB or LDL-P) or estimated by measuring the cholesterol in LDL (LDL-C). The amount of cholesterol inside LDL particles is variable so ApoB and LDL-C often disagree.
22 mar 2019 · Multiple studies have shown that when measurements of LDL cholesterol and LDL particles diverge, LDL particles are the superior biomarker for risk prediction. Jeffrey (Jeff) Meeusen, Ph.D., gives an overview of the new nuclear magnetic resonance (NMR) lipoprotein profile available through Mayo Clinic Laboratories.
12 lip 2022 · NMR LipoProfile, in addition to measuring lipoprotein cholesterol levels, also measures LDL particle number, identifies subsets of individuals who need monitoring, and measures other parameters like insulin resistance markers of systemic inflammation that help predict cardiovascular risk.
12 kwi 2024 · The NMR LipoProfile test is a sophisticated assessment that measures the number, size, and type of lipoprotein particles circulating in our blood. Unlike traditional tests, the NMR LipoProfile provides a comprehensive view, identifying at-risk individuals even when cholesterol levels appear normal.
To simplify and enhance clinical use of NMR lipoprotein particle information, test results are supplied to clinicians in a two-page NMR LipoProfile report, which is organized into four...
The NMR LipoProfile reports individual concentrations of each of the apoB (VLDL, IDL and LDL) and apoA-I (HDL) subparticles in umol/L or nmol/L. The NMR LipoProfile does not report apoB or apoA-I levels, as there is no need for them with the NMR reporting individual particle concentrations. Note that the NMR HDL-P contains only alpha-HDL numbers
