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22 maj 2007 · Nitric oxide (NO) is believed to be the main vasoactive nonadrenergic, noncholinergic neurotransmitter and chemical mediator of penile erection. Released by nerve and endothelial cells in the corpora cavernosa of the penis, NO activates soluble guanylyl cyclase, which increases 3′,5′‐cyclic guanosine monophosphate (cGMP) levels.
- Erectile Function and Sexual Behavior: A Review of the Role of Nitric ...
Nitric oxide produced by NO synthase (NOS) participates in a...
- Erectile Function and Sexual Behavior: A Review of the Role of Nitric ...
11 gru 2021 · Nitric oxide produced by NO synthase (NOS) participates in a complex neural circuit that controls sexual motivation, reward and performance at central level together with other neurotransmitters and neuropeptides.
1 lip 2024 · Molecular studies revealed its sources to be the endothelium of penile vessels and sinusoids as well as nerves terminating in the penis. Erection studies in intact animals next affirmed that NO executes the actual physiologic response of penile erection.
25 cze 2019 · These adaptations include increased expression and activity of nitric oxide synthase, strengthened endothelial function, acute rises in testosterone, decreased stress and anxiety, and improved...
idants on erectile function was greater in men with lower baseline IIEF-EF scores (p<0.001) and over longer treatment durations (p=0.01). In multivariable meta-regression, a lower baseline IIEF-EF score was the only factor associated with a greater treatment effect of antioxida.
10 lis 2011 · Oxidative stress and inflammation, which disrupt nitric oxide (NO) production directly or by causing resistance to insulin, are central determinants of vascular diseases including ED.
1 lip 2006 · Nitric oxide, an evanescent seemingly trivial gaseous chemical, has been quite a force in bringing the sphere of sexual medicine forward. Widely acknowledged at this time is the fact that nitric oxide subserves a fundamental mechanism responsible for the erectile response.
